Student Name
Date
Student Name
Student Name
Student Name
Date
Questions
Student Response
Part I
Original DNA Strand:
3’-T A C C C T T T A G T A G C C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence one:
3’-T A C G C T T T A G T A G C C A T T-5′
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence two:
3’-T A A C C T T T A C T A G G C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
What is the significance of the first and last codons of an mRNA transcript?
Explanation:
What meaning do these mRNA codons have for protein synthesis?
Explanation:
Did the two mutations result in a change in the final proteins? If so, describe the change.
Response/ explanation:
In general, why might a change in amino acid sequence affect protein function?
Explanation:
Part II
Punnett Square
- Chances (%) for healthy child, not a carrier
- Chances (%) for child that is carrier for cystic fibrosis trait
- Chances (%) for child with cystic fibrosis
Fill out/adapt Punnett Square:
______
_____
______
______
- Chances (%) for healthy child, not a carrier:
- % for child that is carrier for cystic fibrosis trait:
- % for child with cystic fibrosis:
Part III: Essay
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?
- Include steps in meiosis that increase variability
- Include the process of fertilization.
Date
Questions
Student Response
Part I
Original DNA Strand:
3’-T A C C C T T T A G T A G C C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence one:
3’-T A C G C T T T A G T A G C C A T T-5′
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence two:
3’-T A A C C T T T A C T A G G C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
What is the significance of the first and last codons of an mRNA transcript?
Explanation:
What meaning do these mRNA codons have for protein synthesis?
Explanation:
Did the two mutations result in a change in the final proteins? If so, describe the change.
Response/ explanation:
In general, why might a change in amino acid sequence affect protein function?
Explanation:
Part II
Punnett Square
- Chances (%) for healthy child, not a carrier
- Chances (%) for child that is carrier for cystic fibrosis trait
- Chances (%) for child with cystic fibrosis
Fill out/adapt Punnett Square:
______
_____
______
______
- Chances (%) for healthy child, not a carrier:
- % for child that is carrier for cystic fibrosis trait:
- % for child with cystic fibrosis:
Part III: Essay
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?
- Include steps in meiosis that increase variability
- Include the process of fertilization.
Date
Student Name
Date
Questions
Student Response
Part I
Original DNA Strand:
3’-T A C C C T T T A G T A G C C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence one:
3’-T A C G C T T T A G T A G C C A T T-5′
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence two:
3’-T A A C C T T T A C T A G G C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
What is the significance of the first and last codons of an mRNA transcript?
Explanation:
What meaning do these mRNA codons have for protein synthesis?
Explanation:
Did the two mutations result in a change in the final proteins? If so, describe the change.
Response/ explanation:
In general, why might a change in amino acid sequence affect protein function?
Explanation:
Part II
Punnett Square
- Chances (%) for healthy child, not a carrier
- Chances (%) for child that is carrier for cystic fibrosis trait
- Chances (%) for child with cystic fibrosis
Fill out/adapt Punnett Square:
______
_____
______
______
- Chances (%) for healthy child, not a carrier:
- % for child that is carrier for cystic fibrosis trait:
- % for child with cystic fibrosis:
Part III: Essay
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?
- Include steps in meiosis that increase variability
- Include the process of fertilization.
Student Name
Date
Questions
Student Response
Part I
Original DNA Strand:
3’-T A C C C T T T A G T A G C C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence one:
3’-T A C G C T T T A G T A G C C A T T-5′
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence two:
3’-T A A C C T T T A C T A G G C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
What is the significance of the first and last codons of an mRNA transcript?
Explanation:
What meaning do these mRNA codons have for protein synthesis?
Explanation:
Did the two mutations result in a change in the final proteins? If so, describe the change.
Response/ explanation:
In general, why might a change in amino acid sequence affect protein function?
Explanation:
Part II
Punnett Square
- Chances (%) for healthy child, not a carrier
- Chances (%) for child that is carrier for cystic fibrosis trait
- Chances (%) for child with cystic fibrosis
Fill out/adapt Punnett Square:
______
_____
______
______
- Chances (%) for healthy child, not a carrier:
- % for child that is carrier for cystic fibrosis trait:
- % for child with cystic fibrosis:
Part III: Essay
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?
- Include steps in meiosis that increase variability
- Include the process of fertilization.
Questions
Student Response
Part I
Original DNA Strand:
3’-T A C C C T T T A G T A G C C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence one:
3’-T A C G C T T T A G T A G C C A T T-5′
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence two:
3’-T A A C C T T T A C T A G G C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
What is the significance of the first and last codons of an mRNA transcript?
Explanation:
What meaning do these mRNA codons have for protein synthesis?
Explanation:
Did the two mutations result in a change in the final proteins? If so, describe the change.
Response/ explanation:
In general, why might a change in amino acid sequence affect protein function?
Explanation:
Part II
Punnett Square
- Chances (%) for healthy child, not a carrier
- Chances (%) for child that is carrier for cystic fibrosis trait
- Chances (%) for child with cystic fibrosis
Fill out/adapt Punnett Square:
______
_____
______
______
- Chances (%) for healthy child, not a carrier:
- % for child that is carrier for cystic fibrosis trait:
- % for child with cystic fibrosis:
Part III: Essay
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?
- Include steps in meiosis that increase variability
- Include the process of fertilization.
Questions
Student Response
Part I
Original DNA Strand:
3’-T A C C C T T T A G T A G C C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence one:
3’-T A C G C T T T A G T A G C C A T T-5′
Transcription (base sequence of RNA):
Translation (amino acid sequence):
Mutated gene sequence two:
3’-T A A C C T T T A C T A G G C A C T-5’
Transcription (base sequence of RNA):
Translation (amino acid sequence):
What is the significance of the first and last codons of an mRNA transcript?
Explanation:
What meaning do these mRNA codons have for protein synthesis?
Explanation:
Did the two mutations result in a change in the final proteins? If so, describe the change.
Response/ explanation:
In general, why might a change in amino acid sequence affect protein function?
Explanation:
Part II
Punnett Square
- Chances (%) for healthy child, not a carrier
- Chances (%) for child that is carrier for cystic fibrosis trait
- Chances (%) for child with cystic fibrosis
Fill out/adapt Punnett Square:
______
_____
______
______
- Chances (%) for healthy child, not a carrier:
- % for child that is carrier for cystic fibrosis trait:
- % for child with cystic fibrosis:
Part III: Essay
How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?
- Include steps in meiosis that increase variability
- Include the process of fertilization.